11th International Conference

Functional Foods and Chronic Inflammation: Science and Practical Application

August 21-23, 2012, University of San Diego, San Diego, California, USA

Conference Program

Tuesday, August 21, 2012


8:00-9:00 am

Conference Registration


9:00-9:15 am

Conference Opening

Conference Chairman and Organizer: Danik M. Martirosyan, PhD, UT Southwestern Medical Center, Dallas, TX, USA 

Co-chairman: Garth Nicolson, PhD, Professor, Institute for Molecular Medicine, S. Laguna Beach, California, USA

Co-chairman: Bharat B. Aggarwal, PhD,  Professor, UT M.D. Anderson Cancer Center, Houston, TX, USA

Conference Moderator: Emma S. Tomlinson Guns, PhD, Vancouver Prostate Center, University of British Columbia, Canada


Session 1. Functional Food Ingredients: Sources and Potential Benefits in Public Health

Session Chair: Jacob Joseph, MD Conference

9:15 - 9:45 am

Searching synbiotics to increase colonic butyrate concentration

Robert W. Li, PhD, Professor, Keynote Speaker,  Research Molecular Biologist/Lead Scientist, USDA, Agricultural Research Service, Belstville, USA.

9:45 - 10:10 am

Resveratrol modulates Sirt-1-mediated osteogenic differentiation of mesenchymal stem cells by repressing of PPAR-γ and stimulation of Cbfa-1 in vitro

Mehdi Shakibaei, PhD, Professor, Ludwig Maximilian University Munich, Munich, Germany

10:10 - 10:30 am

Influences of orally administered recombinant human lactoferrin on systemic and intestinal immune responses in neonatal piglets

Ning Li, PhD, Professor, State Key Laboratory of AgroBiotechnology, China Agricultural University, Beijing, P. R. China

10:30 - 10:50 am



10:50 - 11:10 am

Antiradical and antioxidant activities of different Spirulina platensis extracts against DPPH and ABTS radical assays

Emad A. Shalaby, PhD, Department of Biochemistry, Cairo University, Giza, Egypt




11:10 - 11:30 am

Soybean isoflavones reduce the risk of cancers

Lin Li, PhD candidate, School of Population Health, The University of Western Australia, Crawley, WA, Australia

11:30 - 11:50 pm

A comparative study on the effects of Menstrogol® (dried extracts of celery, saffron and anise) and Mefenamic acid on postpartum after-pain

Simbar Masoumeh, PhD, Department of Reproductive Health and Midwifery, Faculty of Nursing and Midwifery, Shahid Beheshti Medical Science University, Tehran, Iran

11:50 - 12:10 pm

The influence of size and exposure duration of gold nanoparticles on gold nanoparticles levels in several rat tissues in vivo

Mohamed Anwar K Abdelhalim, PhD, Professor, King Saud University, Saudi Arabia

12:10 - 1:10 pm



  1:10 - 1:50 pm

1st Meeting of the Academic Society for Functional Foods and Bioactive Compounds

 Introduction by Danik Martirosyan and Garth  Nicolson

Session 2:  Chronic Inflammation and Modern Disease: Diabetes, Obesity, CVD, Cancer, and other Disorders 

Session Chair: Garth Nicolson, PhD, Professor

1:50 - 2:20 pm

Blood homocysteine levels are significantly reduced with a glycophospholipid formulation plus vitamin B-complex: a retrospective study in older subjects

Garth Nicolson, PhD, Professor, President of Institute for Molecular Medicine,  S. Laguna Beach, California, USA

 2:20 - 2:50 pm

Melanogenesis helps human adipose tissue to withstand low-grade systemic inflammation 

Ancha Baranova, PhD, School of Systems Biology, George Mason University, Fairfax, VA, USA

 2:50 - 3:10 pm



 3:10 - 3:35 pm

Effects of inorganic and organic selenium supplements on survival and cardiac remodeling after myocardial infarction in mice

Jacob Joseph, MD, Cardiology Section, VA Boston Healthcare System, West Roxbury, MA, USA; Harvard Medical School, Boston, MA, USA 

 3:35 - 4:00 pm

Induction of apoptosis in rheumatoid arthritis synovial fibroblasts by triterpenoid-rich fraction of apple peel

Salah-uddin Ahmed, PhD, Assistant Professor of Pharmacology, Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, Ohio, USA

4:00 - 4:25 pm

Enhanced production of  natural bioactive compound tanshinone by metabolically engineered Salvia miltiorrhiza hairy roots

Guoyin Kai, PhD, Professor, Center of Plant Resourec R&D,  Department of Biology, Shanghai Normal University, Shanghai, PR China

4:25 - 4:30 pm







Wednesday,  August 22, 2012



Session 3: Functional Foods and Bioactive Compounds in the Management of Chronic Inflammation

Session Chair: Bruce P. Burnett, PhD

9:00 - 9:35 am

Immune and  metabolic modulation by administration of glycoconjugates comprised of the human milk sugar Lacto-N-fucopentaose III

Donald Harn, PhD, Professor, Keynote Speaker, Department  of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, USA

 9:35 - 10:05 am

Potential of spice-derived nutraceuticals in prevention and treatment of chronic diseases

Bharat B. Aggarwal, PhD, Professor, Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA

10:05 - 10:35 am

Pomegranate fruit extracts inhibit pten-akt signalling pathway in lncap cells without affecting epigenetic pathways

Emma S. Tomlinson Guns, PhD, Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Canada

10:35 - 10: 55 am



10:55 - 11:20 am

Curcuminoids as antioxidants improve red cell survival in patients with Beta-thalassemia-hemoglobin E

Issarang Nuchprayoon, MD, PhD, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

11:20 - 11:45 am

Synergistic effect of non-steroidal anti-inflammatory drug, Lactobacillus rhamnosus GG and Allium sativum on PI3-kinase and Wnt Signaling on DMH induced colon cancer

Manoj Kumar, PhD, Department of Microbiology and Immunology National Institute of Nutrition, ICMR Hyderabad, India

11:45 - 12:10 am

Structure and biological functions of immuno-modulating molecules in wheat grass

Shui-Tein Chen, PhD, Professor, Institute of Biological Chemistry and Genomic Research Center, Academia Sinica, Taipei, Taiwan

12:10 - 1:25 pm




Session 4A. Functional and Medical Foods in the Management of Chronic Diseases

Session Chair: Giulio Pasinetti, MD, PhD, Professor

 1:25 - 2:00 pm

Grape seed extract as a potential novel therapeutic avenue to prevent the spreading of tau pathology

Giulio Pasinetti, MD, PhD, Professor, Mount Sinai School of Medicine, New York, New York, USA

 2:00 - 2:30

Fosteum containing Genistein as an option for management of bone loss with  vasomotor and cardiovascular benefits

Bruce P. Burnett, PhD, Director of Medical Education and S/Regulatory Affairs, Primus Pharmaceuticals, Inc, Scottsdale, AZ, USA

 2:30 - 2:55 pm

Green tea for the prevention of cancer: evidence of clinical epidemiology

Min Zhang, MD, PhD, The University of Western Australia, Perth, WA, Australia

 2:55 - 3:15 pm Refreshments

 3:15 - 3:40 pm

Association between dietary inflammatory score and prognostic outcomes in breast cancer survivors: the WHEL study

Adriana Villasenor, PhD, UCSD Cancer Center, University of California, San Diego, CA, USA

 3:40 - 4:05 pm

Influence of two different n-3 LC PUFA doses on disease activity in patients with rheumatoid arthritis Christine Dawczynski, PhD, Department of Nutritional PhysiologyFriedrich Schiller University of Jena, Jena, Germany

4:05 - 4:25 pm

In-silico prediction of food bioactive peptides

Nora Khaldi, PhD, School of Medicine and Medical Science, University College Dublin, Ireland

 4:25 - 4:30 pm





 Thursday, August 23, 2012


 Session 4B. Functional and Medical Foods in  the Management of Chronic Diseases

  Session chair: Bharat B. Aggarwal, PhD, Professor

9:00 - 9:30 am

Geranium oil for prevention of Parkinson's disease

Anat Elmannl, PhD, Department of Food Quality and Safety, The Volcani Center; Agricultural Research Organization, Israel

9:30 - 9:50 am

Amerliorative potential of Beta vulgaris (l.) on ethanol – mediated hepatotoxicity and oxidative stress: in vitro and in vivo studies

Nilesh K. Jain, PhD, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour Vishwavidyalaya, Sagar, India

 9:50 - 10:10 am

 Effect of wheatgrass on oxidative stress  caused by CCl4 induced hepatotoxicity in  rats

 Satyavati Rana, PhD, Professor, Department of  Gastroenterology, PGIMER, Chandigarh, India

 10:10 - 10:15  Refreshments


Session 5: Research and Development of Functional Food Products

Session Chair: Danik M. Martirosyan, PhD

10:15 - 10:45 am

Anti-Inflammatory activity of an olive polyphenols formulation, review of supporting data

Roberto Crea, PhD, President and CEO, Creagri Inc. Hayward CA, USA

10:45 - 11:10 am

Developing effective meal replacement with good taste, appetite suppression and postprandial energy expenditure stimulation

Harunobu Amagase, PhD, VP, Chief Scientific Officer of Free Life International Inc., Phoenix, AZ, USA

11:10 - 11:35 am

Flavocoxid, a naturally-derived anti-inflammatory with a broad Mechanism of Action for the Management of Osteoarthritis

Bruce P. Burnett, PhD, Director, Departments of Scientific and Clinical Affairs, Primus Pharmaceuticals, Inc, Scottsdale, AZ, USA

11:35 - 12:00 pm

Development of new functional food products rich in omega 3 fatty acids and vitamin C. Danik M. Martirosyan, PhD, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA, Functional Food Center, Dallas, TX, USA

 12:00 - 1:10 pm


1:10 - 2:40 pm

Session 6: Posters Presentation Session and Workshop

2:40 - 3:00 pm

Conference Closing