12th International Conference 

Functional Food Ingredients and Nutraceuticals in Chronic Disease: Science and Practice

November 29 - December 1, 2012, SMU, Dallas, TX, USA

Organized by: Functional Food Center and Department of Biological Sciences, Southern Methodist University, Dallas, TX, USA

Chairman and Conference Organizer: Danik M. Martirosyan, PhD, Department of Internal Medicine, UT Southwestern Medical Center, Dallas TX, USA, Founder of Functional Food CenterDallas, TX, USA

Co-chairman: Steven B. Vik, PhD, Professor and Chair, Department of Biological Sciences, Southern Methodist University, Dallas, TX, USA

Co-chairman: Chandra Mohan, MD, Professor, Walter M. and Helen D. Bader Professorship in Arthritis and Autoimmine Desease Research, UT Southwestern Medical Center at Dallas, TX, USA

Co-chairman: Giulio Maria Pasinetti, MD, PhD, Professor, Saunders Family Chair in Neurology, Director, Center of Excellence for Novel Approaches to Neurotherapeutics Professor of Psychiatry and Neuroscience, Professor of Geriatrics and Adult Development, Department of Neurology and Friedman Brain Institute, The Mount Sinai School of Medicine, New York, NY, USA

Co-chairman: Garth Nicolson, PhD, Professor, Department of Molecular Pathology, President of Institute for Molecular Medicine, S. Laguna Beach, California, USA (A Nobel Prize nominee - Garth Nicolson is the world's leading authority on cellular medicine, author of more than 600 medical and scientific publications)

Conference Moderator: Bruce Burnett, PhD, Primus Pharmaceuticals, LLC, Scottsdale, AZ, USA

Place:  Southern Methodist University (SMU), Dallas, TX, USA

Time:  November 29th – December 1st, 2012

Conference program

Thursday, November 29, 2012

8:00-9:00 am - Conference Registration

9:00 -9:10 am - Conference Opening

Danik M. Martirosyan, PhD, Conference Chairman, Founder of Functional Food Center, Dallas, TX, USA

9:10-9-20 am - Welcome to SMU:
James E. Quick, Associate Vice President for Research, Dean of Graduate Studies, and Professor of Earth Sciences


Session 1:

Functional Food Ingredients: Sources and Potential Benefits in Public Health

Session Chair:

9:20-10:00 am - Spices as functional foods: their role in inflammation associated chronic Diseases.  Keynote Speaker: Bharat Aggarwal, PhD, Professor, Director, Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA

10:00 -10:30 am - Perspectives on flavonoids in chronic disease preventionDouglas Wilson, PhD, School of Medicine Pharmacy and Health, Durham University, Queen’s Campus, Stockton-on-Tees, UK

10:30-10:50 am - Refreshments

10:50-11:25 am - Chemoprevention Adopting A Combined Extract of 5 Natural Products Rich in PPAR Ligands for High Risk Chronic HBV Carriers. Ih-Jen Su, MD, PhD, Professor, Director of National Instute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Town, Taiwan

11:25-11:50 am - “Un Pueblo Tan Dulce”: Understanding the relationship between diabetes, depression, and obesity in Puerto Rico. Shir Lerman, PhD, Student, University of Connecticut, Department of Anthropology, Storrs, Connecticut, USA      

 11:50 -1:00 pm – Lunch

Session 2:

Functional Food Ingredients and Chronic Diseases

Session Chair:

 1:00-1:40 pm - The use of medical foods in treatment regimens for chronic conditions and diseases. Keynote Speaker: Bruce Burnett, PhD, Primus Pharmaceuticals, LLC, Scottsdale, AZ, USA

 1:40-2:15 pm – Nutrition science in the OMICs era. Chandra Mohan, MD, Professor, Department of Internal Medicine, UT Southwestern Medical Center, Dallas TX, USA 

2:15-2:40 pm -Modeling Type II Diabetes in drosophila melanogaster. Sarah Morris and Johannes H. Bauer, PhD, Assistant Professor, Department of Biological Sciences, SMU, Dallas, TX, USA

 2:40-3:00 pm - Refreshments

3:00-3:25 pm - Evaluation of antiproliferative effect and cell cycle arrest on HT29 cells of different plant-derived natural extracts- Correlation of response with composition. Ana Teresa Serra, PhD, Instituto de Biologia Experimental e Tecnológica, Avenida da República, Quinta-do-Marquês, Estação Agronómica Nacional, Oeiras, Portugal

3:25-4:00 pm - The effects of dietary polyunsaturated fatty acids in the prevention of coronary heart disease. Sabrina Hamri-Zeghichi, PhD, Department of Food Sciences, Faculty of Biology, University of Bejaia. Targa Ouzemour, Béjaia, Algeria

4:00-4:25 pm – Green Tea Epigallocatechin-3-gallate treatment ameliorates collagen induced arthritis and lrads to inductionnof IDO producing immunosuppressive M2 macrophages via the Nrf2 antioxidant pathway. Soyoun Min, PhD, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA

4:25-4:30 pm - Closing


Friday, November 30, 2012

Session 3:

 Role of Functional Food Ingredients in Nutrigenomics and Metabolomics

Session Chair:

 9:00-9:35 am - Function of fibers involving the glucose absorption in the small intestine. Toru Takahashi, PhD, Associate professor, Graduate School of Human Environment Science, Fukuoka Women's University, Fukuoka, Japan

9:35-10:05 am - Tumor-suppressive activity of geranylgeraniol in vitro. Huanbiao Mo, PhD, Professor, Department of Nutrition and Food Sciences, Texas Woman's University, Denton, TX, USA

10:05-10:35 am - Dietary restriction, redox state and aging. Svetlana N. Radyuk, PhD, Research Associate Professor, Department of Biological Sciences, Southern Methodist University, Dallas, Texas, USA

10:35-10:55 am - Refreshments

10:55-11:20 am - Role of an aqueous garlic extract to mitigate hypercholesterolemia and hyperglycemia using rabbit experimental modeling. Hafiz Ansar Rasul Suleria, PhD, Functional and Nutraceutical Research Section, National Institute of Food Science and TechnologyUniversity of Agriculture, Faisalabad, Pakistan

Session 4: 

Functional and Medical Foods in the Management of Chronic Diseases

Session Chair:

11:20-12:00 noon - Brain bioactive polyphenols as disease-modfying agents in Alzheimer's Disease. Keynote Speaker:  Giulio Maria Pasinetti, MD, PhD, Professor, Saunders Family Chair in Neurology, Director, Center of Excellence for Novel Approaches to, Department of Neurology and Friedman Brain Institute, The Mount Sinai School of Medicine, New York, NY, USA

12:00-1:15 pm – Lunch

1:15-1:45 pm - Cardio-protective factors in kiwifruits.  Asim Duttaroy, MD, PhD, Professor, Department of Nutrition, Faculty of Medicine, University of Oslo, Oslo, Norway

1:45 pm-2:15 pm - Resveratrol targets mitochondria for cancer prevention and therapy. Dhyan Chandra, PhD, Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, NY, USA

2:15-2:35 pm - Refreshments

2:35-3:05 pm - Amelioration of nephritis by Curcumin in two mouse modelsTianfu Wu, PhD, Department of Internal medicine, UT Southwestern Medical Center, Dallas, TX, USA

3:05-3:35 pm Can a functional food treat hyperphosphatemia in Chronic Kidney Disease? J. Ruth Wu-Wong, PhD, Vidasym, Chicago, IL, USA

3:35-4:05 pm - Maternal bitter melon supplementation reversed tissue inflammatory responses induced by two-generation fructose exposure. Edmund T. S. Li, PhD, Associate Professor, School of Biological Sciences, Kadoorie Building, Faculty of Science, University of Hong Kong, China

4:05 - 4:25 pm - Modulating the vascular behavior of metastatic breast cancer cells byCurcumin treatment. Anna Lisa Palange, PhD, Student, Department of Translational Imaging and Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, TX, USA; Department of Experimental and Clinical Medicine, University of Magna Graecia, Catanzaro, Italy

4:25-4:30 pm - Closing

Saturday, December 1, 2012

Session 5:

Research and Development of Functional and Medical Food Products

Session Chair:

9:00-9:25 am - Lipid based delivery system for bioactives in functional foods. Kristberg Kristbergsson, PhD, Professor, Department of Food Science and Nutrition, School of Health Sciences, University of Iceland, Reykjavík, Iceland

9:25-9:50 am - Comparing different preparations and doses of Rose hip powder in patients with osteoarthritis of the knee: an exploratory randomized active-controlled trial. Robin Christensen, PhD,The Parker Institute, Department of Rheumatology,  Copenhagen University Hospital at Frederiksberg, Copenhagen F, Denmark

 9:50-10:15 am - Hidrox, apropietary formulation of olive polyphenols, with broad range anti-inflammatory efficacy and the development of consumer products for health and wellness. Roberto Crea, PhD, President and CEO, Creagri Inc., Hayward CA, USA

10:15-10:30 am - Refreshments

10:30-10:55 am - Betaine supplementation accelerates liver regeneration after partial hepatectomy via regulation of transsulfuration reactions. Young Chul Kim, PhD, Professor, College of Pharmacy, Seoul National University, Seoul, Korea

10:55-11:20 am Mapping the inhibition site of theaflavins on Respiratory Complex I. Steven B Vik, PhD, Professor and Chair, Department of Biological Sciences, Southern Methodist University, Dallas, TX, US

 11:20 -11:30 pm - Refreshments

Session 6: Poster Presentations 

11:30-12:45 pm - Poster Presentations

12:45-1:00 pm - Conference Closing